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Error in Funding/Support

from ArchNeur - 01 Dec 14

In the Original Investigation entitled “Effect of Leukocyte Telomere Length on Total and Regional Brain Volumes in a Large Population-Based Cohort,” published in the October 2014 issue of JAMA Neurology (2014;71[10]:1247-1254. doi:10.1001/jamaneurol.2014.1926), one of the funding sources was inadvertently omitted from the Funding/Support section. This article was corrected online.



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Incorrect Information in Reply Letter

from ArchNeur - 01 Dec 14

In the Reply Letter titled “The Central Clock in Patients With Parkinson Disease—Reply,” published in the November issue of JAMA Neurology (2014;71[11]:1456-1457), there was incorrect information in the last 2 sentences of the second paragraph. The end of the paragraph should have read as follows: “In contrast to these findings, Bolitho and colleagues3 found increased melatonin secretion and prolonged phase angle of entrainment in medicated patients with PD (n?=?16) but not in unmedicated patien



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JAMA Neurology

from ArchNeur - 01 Dec 14

Mission Statement: The mission of JAMA Neurology is to publish scientific information primarily important for those physicians caring for people with neurologic disorders but also for those interested in the structure and function of the normal and diseased nervous system. These specific aims are (1) to make timely publication of original research of the nervous system, (2) to record observations of single patients or groups of patients that will provide new information and insights, (3) to repo



0

The early antibiotic therapy in septic patients - milestone or sticking point?

from Critical Care Forum - 30 Nov 14

Sepsis is one of the oldest and most elusive syndromes in medicine. Every effort should be made to treat these patients with the best available evidence. As a milestone, empiric antimicrobial therapy is essential in order to reduce morbidity and mortality of septic patients. As a sticking point, the use of broad-spectrum antimicrobial agents may be associated with induction of resistance among common pathogens.



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New insights into how p53 tumor suppressor binds to the human genome

from MNToncology - 30 Nov 14

Scientists from the US Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) have learned new details about how an important tumor-suppressing protein, called p53, binds to the...



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Scientists develop process that turns human waste into rocket fuel

from MNTgastro - 30 Nov 14

Researchers from the University of Florida have found a way to convert human waste into a biogas - a mix of methane and carbon dioxide - that can power a space shuttle.



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Simple blood test could inform head injury-related "return to play" decisions

from MNTneuro - 30 Nov 14

New Penn Medicine research has found that elevated levels in the blood of the brain-enriched protein calpain-cleaved aII-spectrin N-terminal fragment, known as SNTF, shortly after sports-related...



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Scientists find a way to prevent, reverse chronic pain

from MNTneuro - 30 Nov 14

Researchers found that chronic pain could be halted or reversed in rodents by activating a receptor called A3 with a small adenosine molecule.



0

DNA transcription linked to disease-causing expansions

from MNThunting - 30 Nov 14

Researchers in human genetics have known that long nucleotide repeats in DNA lead to instability of the genome and ultimately to human hereditary diseases such Freidreich's ataxia and Huntington's...



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Accuracy of invasive arterial pressure monitoring in cardiovascular patients: an observational study

from Critical Care Forum - 30 Nov 14

IntroductionCritically ill patients and patients undergoing high-risk and major surgery, are instrumented with intra-arterial catheters and invasive blood pressure is considered the ?gold standard? for arterial pressure monitoring. Nonetheless, artifacts due to inappropriate dynamic response of the fluid-filled monitoring systems may lead to clinically relevant differences between actual and displayed pressure values. We sought to analyze the incidence and causes of resonance/underdamping phenom



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A retrospective analysis of reported errata in five leading medical journals in 2012.

from Lancet - 30 Nov 14

A retrospective analysis of reported errata in five leading medical journals in 2012. J Community Hosp Intern Med Perspect. 2014;4(5):25738 Authors: Bhatt VR, Aryal MR, Panta S, Mosalpuria K, Armitage JO Abstract Background: Although medical publications are frequently used as the source of information, the prevalence of errata remains unclear. The objective of this study was to examine peer-review and publication processes of medical journals



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T-wave inversions in athletes: a sheep in wolf's clothing?

from Heart - 30 Nov 14

T-wave inversions in athletes: a sheep in wolf's clothing? Heart. 2014 Nov 28; Authors: Wasfy MM, Baggish AL PMID: 25432978 [PubMed - as supplied by publisher]



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Response to comment on: The infective endocarditis team: recommendations from an international working group by San Roman et al.

from Heart - 30 Nov 14

Response to comment on: The infective endocarditis team: recommendations from an international working group by San Roman et al. Heart. 2014 Nov 28; Authors: Chambers JB, Sandoe J, Ray S, Prendergast B, Arden C, Wilson J, Campbell B, Gohlke-Baerwolf C, Mestres CA, Rosenhek R, Pibarot P, Otto CM PMID: 25432977 [PubMed - as supplied by publisher]



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Effects of Niacin, Statin, and Fenofibrate on Circulating Proprotein Convertase Subtilisin/Kexin Type 9 Levels in Patients With Dyslipidemia.

from Am J Cardiol - 30 Nov 14

Effects of Niacin, Statin, and Fenofibrate on Circulating Proprotein Convertase Subtilisin/Kexin Type 9 Levels in Patients With Dyslipidemia. Am J Cardiol. 2014 Oct 31; Authors: Khera AV, Qamar A, Reilly MP, Dunbar RL, Rader DJ Abstract Recent trials demonstrated substantial improvement in lipid parameters with inhibition of proprotein convertase subtilisin-like/kexin type 9 (PCSK9). Although statins and fibrates have been reported to increase



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Frequency of High-Risk Patients Not Receiving High-Potency Statin (from a Large Managed Care Database).

from Am J Cardiol - 30 Nov 14

Frequency of High-Risk Patients Not Receiving High-Potency Statin (from a Large Managed Care Database). Am J Cardiol. 2014 Oct 30; Authors: Rodriguez F, Olufade T, Heithoff K, Friedman HS, Navaratnam P, Foody JM Abstract We examined trends in low-density lipoprotein cholesterol (LDL-C) goal attainment in high-risk patients and use of high-potency statins (HPS) in a large, managed-care database from 2004 to 2012. The 2013 American Heart Associat



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Value of the "TAVI2-SCORe" Versus Surgical Risk Scores for Prediction of One Year Mortality in 511 Patients Who Underwent Transcatheter Aortic Valve Implantation.

from Am J Cardiol - 30 Nov 14

Value of the "TAVI2-SCORe" Versus Surgical Risk Scores for Prediction of One Year Mortality in 511 Patients Who Underwent Transcatheter Aortic Valve Implantation. Am J Cardiol. 2014 Oct 29; Authors: Debonnaire P, Fusini L, Wolterbeek R, Kamperidis V, van Rosendael P, van der Kley F, Katsanos S, Joyce E, Tamborini G, Muratori M, Gripari P, Bax JJ, Marsan NA, Pepi M, Delgado V Abstract A bedside-available transcatheter aortic valve implantation (



0

From Acute Decompensated to Chronic Heart Failure.

from Am J Cardiol - 30 Nov 14

From Acute Decompensated to Chronic Heart Failure. Am J Cardiol. 2014 Dec 15;114(12):1923-1929 Authors: Patel SR, Piña IL Abstract An acute decompensation of heart failure resulting in hospital admission represents a critical juncture in the natural history of the disease, as evidenced by poor mortality and readmission outcomes after hospital discharge. For this reason, a number of new short-term vasoactive therapies have been or are being test



0

Comparison by magnetic resonance phase contrast imagingof pulse-wave velocity in patients with single ventricle who have reconstructed aortas versus those without.

from Am J Cardiol - 30 Nov 14

Comparison by magnetic resonance phase contrast imagingof pulse-wave velocity in patients with single ventricle who have reconstructed aortas versus those without. Am J Cardiol. 2014 Dec 15;114(12):1902-7 Authors: Fogel MA, Li C, Nicolson SC, Spray TL, Gaynor JW, Fuller S, Keller MS, Harris MA, Yoganathan AP, Whitehead KK Abstract Pulse-wave velocity (PWV), a measure of arterial stiffness, is a known independent risk factor for cardiovascular e



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Relation between playing position and coronary artery calcium scores in retired national football league players.

from Am J Cardiol - 30 Nov 14

Relation between playing position and coronary artery calcium scores in retired national football league players. Am J Cardiol. 2014 Dec 15;114(12):1836-40 Authors: Basra SS, Pokharel Y, Hira RS, Bandeali SJ, Nambi V, Deswal A, Nasir K, Martin SS, Vogel RA, Roberts AJ, Ballantyne CM, Virani SS Abstract Retired National Football League (NFL) linemen have an increased prevalence of risk factors for atherosclerosis and have an increased risk of ca



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Prophylactic intra-aortic balloon counterpulsation in cardiac surgery: it is time for clear evidence

from Critical Care Forum - 29 Nov 14

In the previous issue of Critical Care, Yu and colleagues report increased morbidity and mortality in patients after myocardial infarction undergoing prophylactic intra-aortic balloon pump support before coronary artery bypass graft surgery. The impact of prophylactic intra-aortic balloon pump implantation before coronary artery bypass graft therapy still is controversially debated. However, Yu and colleagues emphasize further discussion and substantiate the need for a prospective randomized con



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New ways identified to drain cancer's 'fuel tank'

from MNToncology - 29 Nov 14

Cancer stem cells are particularly difficult to eradicate and are at the heart of why it is so hard to more effectively treat cancer patients, as the post-treatment survival of cancer stem cells...



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Researchers are developing a noninvasive test for endometriosis

from MNTendo - 29 Nov 14

Researchers at UC San Francisco have identified patterns of genetic activity that can be used to diagnose endometriosis and its severity, a finding that may offer millions of women an alternative to...



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Could the key to a good memory be found in our genes?

from MNTneuro - 29 Nov 14

An international collaboration has yielded info on specific genes that are linked to worse memory later in life, potentially predicting who will experience memory loss.



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All obese patients with type 2 diabetes should be assessed for bariatric surgery, says NICE.

from Diabetes abs. - 29 Nov 14

All obese patients with type 2 diabetes should be assessed for bariatric surgery, says NICE. BMJ. 2014;349:g7246 Authors: Wise J PMID: 25428799 [PubMed - in process]



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Joint UK societies' 2014 consensus statement on renal denervation for resistant hypertension.

from Heart - 29 Nov 14

Joint UK societies' 2014 consensus statement on renal denervation for resistant hypertension. Heart. 2014 Nov 27; Authors: Lobo MD, de Belder MA, Cleveland T, Collier D, Dasgupta I, Deanfield J, Kapil V, Knight C, Matson M, Moss J, Paton JF, Poulter N, Simpson I, Williams B, Caulfield MJ Abstract Resistant hypertension continues to pose a major challenge to clinicians worldwide and has serious implications for patients who are at increased risk


 

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